Bioseparation and Bioprocessing (Hardcover (Trade Cloth))

Buy Bioseparation and Bioprocessing (Hardcover (Trade Cloth))

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Bioseparation and Bioprocessing (Hardcover (Trade Cloth)) Product Description

Bioseparation and Bioprocessing Dr. Ganapathy Subramanian is a biotechnology consultant with over 30 years experience in both industry and academia, in the application and development of processing, purification methodologies and chromatographic systems for large-scale use in environmental science, food science, perfumery cosmetics and pharmaceuticals. He has also taught extensively in the area of food and medical technology. A chemistry graduate from Madras, India, Dr Subramanian was awarded his Doctorate from the University of Glasgow, for work on natural products, and his main research interests lie in the utilisation of natural material separation processes and bio-conversions. Dr. Subramanian has written and edited a number of books and articles in the field of biotechnology. For the last 10 years, he has been organizing conferences promoting the integration and sharing of knowledge between academia and industry. In this new edition of the only resource to systematically cover all post-production issues, over 70 of the content is new or rewritten in line with the rapidly evolving technology in the field. By combining the experience of academic experts, managers from the pharmaceutical and biotech industry, as well as independent consultants, biological product recovery is viewed from every possible angle, including biosafety and regulatory issues. VOLUME 1 STRATEGY AND DEVELOPMENT Process Development when to start, when to stop Strategies in downstream processing BIOPROCESS AND EARLY DSP Process Development and Optimization for Biotechnology Production Monoclonal Antibodies Dynamics of cellular response to recombinant protein overexpression in Esscherichia coli PREPARATIVE (CHROMATOGRAPHIC) METHODS Ion Exchange Chromatography in Biopharmaceutical Manufacturing Displacement chromatography of biomacromolecules The Purification of Biomolecules by Countercurrent Chromatography Continuous chromatography in the down-stream processing of compounds from biotechnological and natural origin Continuous Annular Chromatography Principles of membrane separation processes Affinity Precipitation VOLUME 2 SPECIFIC BIOPROCESSES AND SEPARATION METHODS Biological fuel cells Removal and Analysis of Contaminants and Impurities High throughput RNAi Emerging technology for functional Genomics Developing an Antibody Purification Process The Many Ways to Purify Plasmis DNA Choosing the right purification strategy based on the downstream application Advanced Fractionation methods and analysis for proteomics applications SAFETY, QUALITY CONTROL, VALIDATION AND REGUATORY CONSIDERATIONS Biosafety The Manufacture of Gene Therapy Products and Viral Vaccines The Virus and Prion safety of Biopharmaceuticals Protein Glycosylation Analysis and Characterization High Throughput glycoanalysis for use in Bioprocessing Quality Control of Impantable Drug Delivery Systems ANALYTICAL METHODS AND TECHNOLOGIES Polymerase Chain Reaction an Analytical Tool in Bioprocessing El

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